MED17 anticorps (Middle Region)

N° du produit ABIN953370

Détail du produit anti-MED17 anticorps

Antigène: MED17 (Mediator Complex Subunit 17 (MED17))

Épitope: AA 331-361, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED17 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human MED17 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 331-361 amino acids from the Central region of human MED17

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MED17

Antigène: MED17 (Mediator Complex Subunit 17 (MED17))

Autre désignation: MED17 (MED17 Produits)

Synonymes: anticorps crsp6, anticorps CRSP6, anticorps CRSP77, anticorps DRIP80, anticorps TRAP80, anticorps 77kDa, anticorps C330002H14Rik, anticorps Crsp6, anticorps Trap80, anticorps mediator of RNA polymerase II transcription subunit 17, anticorps mediator complex subunit 17, anticorps mediator complex subunit 17 L homeolog, anticorps AOR_1_2446154, anticorps VDBG_01663, anticorps med17, anticorps med17.L, anticorps MED17, anticorps Med17

Sujet: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.Synonyms: ARC77, Activator-recruited cofactor 77 kDa component, CRSP complex subunit 6, CRSP6, Cofactor required for Sp1 transcriptional activation subunit 6, DRIP77, DRIP80, Mediator complex subunit 17, Mediator of RNA polymerase II transcription subunit 17, TRAP80, Thyroid hormone receptor-associated protein complex 80 kDa component, Transcriptional coactivator CRSP77, Vitamin D3 receptor-interacting protein complex 80 kDa component

Poids moléculaire: 72890 Da

ID gène: 9440

NCBI Accession: NP_004259

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha