MED7 anticorps (Middle Region)
Aperçu rapide pour MED7 anticorps (Middle Region) (ABIN953378)
Antigène
Voir toutes MED7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 90-119, Middle Region
-
Specificité
- This antibody recognizes Human MED7 (Center).
-
Purification
- Protein A column, followed by peptide affinity purification
-
Immunogène
- KLH conjugated synthetic peptide between 90-119 amino acids from the Central region of human MED7
-
Isotype
- Ig Fraction
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.25 mg/mL
-
Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- MED7 (Mediator Complex Subunit 7 (MED7))
-
Autre désignation
- MED7
-
Sujet
- The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].Synonyms: ARC34, Activator-recruited cofactor 34 kDa component, CRSP complex subunit 9, CRSP9, Cofactor required for Sp1 transcriptional activation subunit 9, Mediator complex subunit 7, Mediator of RNA polymerase II transcription subunit 7, RNA polymerase transcriptional regulation mediator subunit 7 homolog, Transcriptional coactivator CRSP33
-
Poids moléculaire
- 27245 Da
-
ID gène
- 9443
-
NCBI Accession
- NP_001094286
-
Pathways
- Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
Antigène
-