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Melanophilin anticorps (C-Term)

MLPH Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN953384
  • Antigène Voir toutes Melanophilin (MLPH) Anticorps
    Melanophilin (MLPH)
    Épitope
    • 10
    • 8
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    AA 540-569, C-Term
    Reactivité
    • 35
    • 9
    • 3
    • 1
    Humain
    Hôte
    • 35
    • 4
    • 1
    Lapin
    Clonalité
    • 38
    • 2
    Polyclonal
    Conjugué
    • 18
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Melanophilin est non-conjugé
    Application
    • 30
    • 21
    • 21
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody recognizes Melanophilin / MLPH at C-term.
    Réactivité croisée (Details)
    Species reactivity (tested):Human
    Purification
    Purified through a Protein A column followed by peptide affinity purification
    Immunogène
    Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 540-569aa) of human Melanophilin.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MLPH Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    Melanophilin (MLPH)
    Autre désignation
    Melanophilin (MLPH Produits)
    Synonymes
    anticorps MGC155106, anticorps LOC100222096, anticorps 2210418F23Rik, anticorps 5031433I09Rik, anticorps AW228792, anticorps D1Wsu84e, anticorps Slac-2a, anticorps l(1)-3Rk, anticorps l1Rk3, anticorps ln, anticorps SLAC2-A, anticorps melanophilin, anticorps MLPH, anticorps mlph, anticorps Mlph
    Sujet
    The MLPH gene encodes a member of the exophilin subfamily of Rab effector proteins, Melanophilin. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.Synonyms: Exophilin-3, Leaden protein, Ln, Mlph, Slac2a, Slp homolog lacking C2 domains a, Synaptotagmin-like protein 2a
    ID gène
    79083
    NCBI Accession
    NP_001035932
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