MLH1 anticorps (Middle Region)
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- Antigène Voir toutes MLH1 Anticorps
- MLH1 (MutL Homolog 1 (MLH1))
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Épitope
- AA 459-488, Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MLH1 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
- Specificité
- This antibody recognizes MLH1.
- Réactivité croisée (Details)
- Species reactivity (tested):Human
- Purification
- Purified through a Protein A column followed by peptide affinity purification
- Immunogène
- Synthetic peptide - KLH conjugated - corresponding to the central region (between 459-488aa) of human MLH1.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product MLH1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) Sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- MLH1 (MutL Homolog 1 (MLH1))
- Autre désignation
- MLH1 (MLH1 Produits)
- Synonymes
- anticorps CG11482, anticorps Dmel\\CG11482, anticorps dmlh-1, anticorps dmlh1, anticorps zgc:66301, anticorps MLH1, anticorps LOC100232198, anticorps 1110035C23Rik, anticorps AI317206, anticorps AI325952, anticorps AI561766, anticorps COCA2, anticorps FCC2, anticorps HNPCC, anticorps HNPCC2, anticorps hMLH1, anticorps mutL homolog 1, anticorps CG11482 gene product from transcript CG11482-RB, anticorps mutL homolog 1 S homeolog, anticorps mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), anticorps DNA mismatch repair protein Mlh1, anticorps MLH1, anticorps Mlh1, anticorps mlh1.S, anticorps mlh1, anticorps LOC588545
- Sujet
- The MLH1 gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.Synonyms: COCA2, DNA mismatch repair protein Mlh1
- ID gène
- 4292
- NCBI Accession
- NP_000240
- Pathways
- Réparation de l'ADN, Production of Molecular Mediator of Immune Response
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