MRPS15 anticorps (Middle Region)
Aperçu rapide pour MRPS15 anticorps (Middle Region) (ABIN953517)
Antigène
Voir toutes MRPS15 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 123-153, Middle Region
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Specificité
- This antibody recognizes human MRPS15.
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Purification
- Purified through a Protein A column followed by peptide affinity purification
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Immunogène
- Synthetic peptide - KLH conjugated - corresponding to the central region (between 123-153aa) of human MRPS15.
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MRPS15 (Mitochondrial Ribosomal Protein S15 (MRPS15))
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Autre désignation
- MRPS15
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Sujet
- Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The MRPS15 gene encodes a 28S subunit protein that belongs to the ribosomal protein S15P family. The encoded protein is more than two times the size of its E. coli counterpart, with the 12S rRNA binding sites conserved. Between human and mouse, the encoded protein is the least conserved among small subunit ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 15q and 19q.Synonyms: 28S ribosomal protein S15, DC37, RPMS15, S15mt, mitochondrial
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Poids moléculaire
- 29842 Da
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ID gène
- 64960
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NCBI Accession
- NP_112570
Antigène
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