MUL1 anticorps (C-Term)

N° du produit ABIN953547

Détail du produit anti-MUL1 anticorps

Antigène: MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))

Épitope: AA 279-309, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUL1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes MUL1 / RNF218 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogène: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 279-309aa) of human MUL1 / RNF218

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MUL1

Antigène: MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))

Autre désignation: MUL1 / RNF218 (MUL1 Produits)

Synonymes: anticorps C1orf166, anticorps GIDE, anticorps MAPL, anticorps MULAN, anticorps RNF218, anticorps RP11-401M16.2, anticorps mul1, anticorps zgc:92166, anticorps 0610009K11Rik, anticorps AV000801, anticorps Gide, anticorps RGD1309944, anticorps im:7146383, anticorps zgc:165594, anticorps mitochondrial E3 ubiquitin protein ligase 1, anticorps mitochondrial E3 ubiquitin protein ligase 1 L homeolog, anticorps mitochondrial E3 ubiquitin protein ligase 1a, anticorps mitochondrial ubiquitin ligase activator of NFKB 1, anticorps mitochondrial E3 ubiquitin protein ligase 1b, anticorps MUL1, anticorps mul1.L, anticorps mul1a, anticorps Mul1, anticorps mul1b

Sujet: E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.Synonyms: C1orf166, E3 ubiquitin-protein ligase MUL1, GIDE, Growth inhibition and death E3 ligase, MAPL, MULAN, Mitochondrial ubiquitin ligase activator of NFKB 1, Mitochondrial-anchored protein ligase, Putative NF-kappa-B-activating protein 266, RING finger protein 218

ID gène: 79594

NCBI Accession: NP_078820

Pathways: Positive Regulation of Endopeptidase Activity