MUTYH anticorps (Middle Region)
Aperçu rapide pour MUTYH anticorps (Middle Region) (ABIN953552)
Antigène
Voir toutes MUTYH AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 352-381, Middle Region
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Specificité
- This antibody recognizes MUTYH.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse
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Purification
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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Immunogène
- Synthetic peptide - KLH conjugated - corresponding to the central region (between 352-381aa) of human MUTYH.
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MUTYH (MutY Homolog (E. Coli) (MUTYH))
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Autre désignation
- MUTYH
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Sujet
- MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair and initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.Synonyms: A/G-specific adenine DNA glycosylase, MYH, MutY homolog
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ID gène
- 4595
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NCBI Accession
- NP_001041636
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Pathways
- Réparation de l'ADN
Antigène
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