PIK3AP1 anticorps (C-Term)
Aperçu rapide pour PIK3AP1 anticorps (C-Term) (ABIN954143)
Antigène
Voir toutes PIK3AP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 646-676, C-Term
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Specificité
- This antibody recognizes PIK3AP1 at C-term.
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Purified through a Protein A column followed by peptide affinity purification
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Immunogène
- Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 646-676aa) of human PIK3AP1.
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))
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Autre désignation
- PIK3AP1
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Sujet
- PIK3AP1 is involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. It couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. PIK3AP1 seems to have a complementary role with CD19 in PI3K activation (By similarity) and is may be involved in the survival of mature B cells via activation of REL (By similarity).Synonyms: B-cell adapter for phosphoinositide 3-kinase, BCAP, Phosphoinositide 3-kinase adapter protein 1
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ID gène
- 118788
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NCBI Accession
- NP_689522
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Pathways
- Activation of Innate immune Response, BCR Signaling, L'effet Warburg
Antigène
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