PRUNE anticorps
Aperçu rapide pour PRUNE anticorps (ABIN954343)
Antigène
Voir toutes PRUNE AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody recognizes PRUNE
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Protein A Chromatography
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Immunogène
- Recombinant protein.
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Isotype
- IgG2a
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.2
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PRUNE (Prune Exopolyphosphatase (PRUNE))
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Autre désignation
- PRUNE
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Sujet
- PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin. Human prune (h-prune), a phosphoesterase DHH family appertaining protein, physically interacts with nm23-H1, a metastasis suppressor gene. h-prune is involved in cellular motility and metastasis formation. Metastatic breast cancers were found to overexpress h-prune, h-prune was also found to be highly expressed in colorectal and pancreatic cancers. Hence h-prune is considered useful as a marker for tumor aggressiveness.Synonyms: DRES-17, DRES17, Drosophila-related expressed sequence 17, HTcD37, Protein prune homolog, hPrune
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ID gène
- 58497
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NCBI Accession
- NP_067045
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UniProt
- Q86TP1
Antigène
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