RAD23B anticorps (N-Term)

N° du produit ABIN954431

L’anticorps anti-RAD23B Polyclonal Lapin est utilisé pour la détection de RAD23B dans des échantillons de Humain. Il a été validé pour WB et EIA.

Aperçu rapide pour RAD23B anticorps (N-Term) (ABIN954431)

Antigène: RAD23B (RAD23 Homolog B (RAD23B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD23B est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-RAD23B anticorps

Épitope: AA 10-40, N-Term

Specificité: This antibody recognizes Human RAD23B (N-term).

Purification: Affinity Chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 10-40 amino acids from the N-terminal region of Human RAD23B.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur RAD23B

Antigène: RAD23B (RAD23 Homolog B (RAD23B))

Autre désignation: RAD23B

Sujet: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.Synonyms: HR23B, UV excision repair protein RAD23 homolog B, XP-C repair-complementing complex 58 kDa protein

Poids moléculaire: 43171 Da

ID gène: 5887

NCBI Accession: NP_002865

Pathways: Réparation de l'ADN