PCGF2 anticorps (Middle Region)

N° du produit ABIN954565

Cet anticorps Lapin Polyclonal détecte spécifiquement PCGF2 dans WB et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PCGF2 anticorps (Middle Region) (ABIN954565)

Antigène: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCGF2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-PCGF2 anticorps

Épitope: AA 120-150, Middle Region

Specificité: This antibody recognizes RNF110 / PCGF2.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogène: Synthetic peptide - KLH conjugated - corresponding to the central region (between 120-150aa) of human RNF110 / PCGF2.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Détails sur PCGF2

Antigène: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Autre désignation: RNF110 / PCGF2

Sujet: The Polycomb group RING finger protein 2 encoded by the PCGF2 gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.Synonyms: DNA-binding protein Mel-18, MEL18, PCGF2, Polycomb group RING finger protein 2, RING finger protein 110, RNF110, ZNF144, Zinc finger protein 144

ID gène: 7703

NCBI Accession: NP_009075

Pathways: Chromatin Binding