AANAT anticorps (N-Term)

N° du produit ABIN954733

Cet anticorps Lapin Polyclonal détecte spécifiquement AANAT dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour AANAT anticorps (N-Term) (ABIN954733)

Antigène: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AANAT est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-AANAT anticorps

Épitope: AA 33-63, N-Term

Specificité: This antibody reacts to Serotonin acetylase.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 33~63 amino acids from the N-terminal region of human AANAT

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur AANAT

Antigène: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Autre désignation: Serotonin Acetylase

Sujet: AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.Synonyms: AA-NAT, AANAT, Aralkylamine N-acetyltransferase, SNAT, Serotonin N-acetyltransferase

ID gène: 15

NCBI Accession: NP_001079

Pathways: Photoperiodism