SH3BP2 anticorps (Middle Region)
Aperçu rapide pour SH3BP2 anticorps (Middle Region) (ABIN954791)
Antigène
Voir toutes SH3BP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 150-180, Middle Region
-
Specificité
- Recognizes SH3BP2 (Center).
-
Purification
- Protein A column followed by peptide Affinity purification
-
Immunogène
- KLH conjugated synthetic peptide between 150-180 amino acids from the Central region of Human SH3BP2 Genename: SH3BP2
-
Isotype
- Ig Fraction
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.25 mg/mL
-
Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
-
Autre désignation
- SH3BP2
-
Sujet
- The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: 3BP-2, 3BP2, SH3 domain-binding protein 2, SH3BP-2
-
ID gène
- 6452
-
NCBI Accession
- NP_001116153
-
Pathways
- TCR Signaling
Antigène
-