FAM33A anticorps (N-Term)

N° du produit ABIN954814

Cet anticorps Lapin Polyclonal détecte spécifiquement FAM33A dans WB, IHC (p) et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour FAM33A anticorps (N-Term) (ABIN954814)

Antigène: FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM33A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-FAM33A anticorps

Épitope: AA 16-45, N-Term

Specificité: This antibody recognizes Human SKA2 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 16-45 amino acids from the N-terminal region of Human SKA2 Genename: SKA2

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FAM33A

Antigène: FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))

Autre désignation: SKA2

Sujet: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it is required for SKA1 localization.Synonyms: FAM33A, Spindle and kinetochore-associated protein 2

Poids moléculaire: 14188 Da

ID gène: 348235

NCBI Accession: NP_872426

Pathways: M Phase