SNX13 anticorps (C-Term)
Aperçu rapide pour SNX13 anticorps (C-Term) (ABIN954885)
Antigène
Voir toutes SNX13 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 779-807, C-Term
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Specificité
- This antibody detects human SNX13 at C-term.
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Purified through a protein A column; followed by peptide affinity purification.
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Immunogène
- Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 779-807aa) of human Sorting nexin-13 (SNX13).
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SNX13 (Sorting Nexin 13 (SNX13))
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Autre désignation
- Sorting Nexin-13 (SNX13)
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Sujet
- SNX13 gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.Synonyms: KIAA0713, RGS domain- and PHOX domain-containing protein
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ID gène
- 23161
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NCBI Accession
- NP_055947
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
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