SPG20 anticorps (C-Term)

N° du produit ABIN954907

Détail du produit anti-SPG20 anticorps

Antigène: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Épitope: AA 490-519, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPG20 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human

Purification: Affinity Chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 490-519 amino acids from the C-terminal region of Human SPG20 Genename: SPG20

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Détails sur SPG20

Antigène: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Autre désignation: Spartin / SPG20 (SPG20 Produits)

Synonymes: anticorps SPARTIN, anticorps TAHCCP1, anticorps AI840044, anticorps C79168, anticorps mKIAA0610, anticorps spartin, anticorps Spg20, anticorps spg20a, anticorps zgc:172059, anticorps spg20b, anticorps zgc:153766, anticorps spartin, anticorps spastic paraplegia 20, spartin (Troyer syndrome) homolog (human), anticorps spartin a, anticorps spartin b, anticorps SPART, anticorps Spg20, anticorps Spart, anticorps sparta, anticorps spartb

Sujet: SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome)Synonyms: KIAA0610, Spastic paraplegia 20 protein, TAHCCP1, Trans-activated by hepatitis C virus core protein 1

Poids moléculaire: 72833 Da

ID gène: 23111

NCBI Accession: NP_001135766

Pathways: Regulation of Cell Size, SARS-CoV-2 Protein Interactome