STAR anticorps (Middle Region)
Aperçu rapide pour STAR anticorps (Middle Region) (ABIN954970)
Antigène
Voir toutes STAR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 87-117, Middle Region
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Specificité
- This antibody recognizes Human STAR (Center).
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Purification
- Affinity Chromatography on Protein A
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Immunogène
- KLH conjugated synthetic peptide between 87-117 amino acids from the Central region of Human STAR
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- STAR (Steroidogenic Acute Regulatory Protein (STAR))
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Autre désignation
- STAR / STARD1
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Sujet
- The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13Synonyms: START domain-containing protein 1, Steroidogenic acute regulatory protein mitochondrial
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Poids moléculaire
- 31914 Da
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ID gène
- 6770
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NCBI Accession
- NP_000340
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Pathways
- Metabolism of Steroid Hormones and Vitamin D, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis
Antigène
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