TGIF1 anticorps (Middle Region)

N° du produit ABIN955179

Cet anticorps anti-TGIF1 est un anticorps Lapin Polyclonal détectant TGIF1 dans WB et EIA. Adapté pour Humain et Souris.

Aperçu rapide pour TGIF1 anticorps (Middle Region) (ABIN955179)

Antigène: TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TGIF1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-TGIF1 anticorps

Épitope: AA 215-245, Middle Region

Specificité: This antibody detects TGIF1 (Center).

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogène: KLH conjugated synthetic peptide between 215-245 amino acids from the Central region of human TGIF1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Détails sur TGIF1

Antigène: TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

Autre désignation: TGIF1

Sujet: The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described.Synonyms: 5'-TG-3'-interacting factor 1, Homeobox protein TGIF1, TGIF

ID gène: 7050

NCBI Accession: NP_003235

Pathways: Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation