NKX2-1 anticorps (N-Term)

N° du produit ABIN955203

Cet anticorps anti-NKX2-1 est un anticorps Lapin Polyclonal détectant NKX2-1 dans WB, FACS et EIA. Adapté pour Humain.

Aperçu rapide pour NKX2-1 anticorps (N-Term) (ABIN955203)

Antigène: NKX2-1 (NK2 Homeobox 1 (NKX2-1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NKX2-1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Détail du produit anti-NKX2-1 anticorps

Épitope: AA 1-30, N-Term

Specificité: This antibody recognizes human TTF1 / NKX2A at N-term.

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogène: Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 1-30aa) of human NKX2-1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur NKX2-1

Antigène: NKX2-1 (NK2 Homeobox 1 (NKX2-1))

Autre désignation: TTF1 / NKX2A

Sujet: The NKX2-1 gene encodes a protein initially identified as a thyroid-specific transcription factor (TTF). TTF1 binds to thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: Homeobox protein NK-2 homolog A, Homeobox protein Nkx-2.1, NKX2-1, Nkx-2.1, TITF1, TTF-1, Thyroid nuclear factor 1, Thyroid transcription factor 1

Poids moléculaire: 38596 Da

ID gène: 7080

NCBI Accession: NP_001073136

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour