TIE1 anticorps (AA 22-748)

N° du produit ABIN955208

Détail du produit anti-TIE1 anticorps

Antigène: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Épitope: AA 22-748

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIE1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée (Details): Species reactivity (tested):Human and Mouse.

Purification: Protein A Chromatography

Immunogène: Highly pure (>95%) recombinant Mouse soluble TIE-1 (Ser22-Ala748) derived from Insect cells.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2

Stock: 4 °C/-20 °C

Stockage commentaire: The lyophilized antibody is stable at RT for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C. Avoid repeated freeze-thaw cycles!

Date de péremption: 6 months

Détails sur TIE1

Antigène: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Autre désignation: TIE1 (TIE1 Produits)

Synonymes: anticorps JTK14, anticorps TIE, anticorps D430008P04Rik, anticorps tie-1, anticorps tyrosine kinase with immunoglobulin like and EGF like domains 1, anticorps tyrosine kinase with immunoglobulin-like and EGF-like domains 1, anticorps tyrosine-protein kinase receptor Tie-1, anticorps endothelium-specific receptor tyrosine kinase 1, anticorps TIE1, anticorps Tie1, anticorps CpipJ_CPIJ018933, anticorps tie1

Sujet: TIE-1 (tyrosine kinase with Ig and EGF homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis.Synonyms: TIE, Tie-1, Tyrosine-protein kinase receptor Tie-1

ID gène: 10090

Pathways: Signalisation RTK