TNIP1 anticorps (C-Term)
Aperçu rapide pour TNIP1 anticorps (C-Term) (ABIN955281)
Antigène
Voir toutes TNIP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 454-482, C-Term
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Specificité
- This antibody detects TNIP1 (C-term).
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Protein A column followed by peptide affinity purification
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Immunogène
- KLH conjugated synthetic peptide between 454-482 amino acids from the C-terminal region of human TNIP1
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))
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Autre désignation
- TNIP1
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Sujet
- Interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP-or TRAF2-mediated transactivation signal (By similarity). Increases cell surface CD4(T4) antigen expression. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production.Synonyms: HIV-1 Nef-interacting protein, KIAA0113, NAF1, Nef-associated factor 1, Nip40-1, TNFAIP3-interacting protein 1, VAN, Virion-associated nuclear shuttling protein
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ID gène
- 10318
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NCBI Accession
- NP_006049
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Pathways
- Activation of Innate immune Response
Antigène
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