XDH anticorps (N-Term)

N° du produit ABIN955594

Cet anticorps Lapin Polyclonal détecte spécifiquement XDH dans WB, IHC (p) et EIA. Il présente une réactivité envers Humain et Souris et a été mentionné dans 1 publication.

Aperçu rapide pour XDH anticorps (N-Term) (ABIN955594)

Antigène: XDH (Xanthine Dehydrogenase (XDH))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XDH est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-XDH anticorps

Épitope: AA 213-242, N-Term

Specificité: This antibody detects Xanthine dehydrogenase/oxidase (N-term).

Réactivité croisée (Details): Species reactivity (tested):Human, mouse.

Purification: Protein A column followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 213~242 amino acids from the N-terminal region of human XDH

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-XDH (ABIN955594)

Ross, Katzov-Eckert, Dubé, Brooks, Rassekh, Barhdadi, Feroz-Zada, Visscher, Brown, Rieder, Rogers, Phillips, Carleton, Hayden: "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy." dans: Nature genetics, Vol. 41, Issue 12, pp. 1345-9, (2009) (PubMed).

Détails sur XDH

Antigène: XDH (Xanthine Dehydrogenase (XDH))

Autre désignation: XDH

Sujet: XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. This protein can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.Synonyms: Xanthine dehydrogenase/oxidase

ID gène: 7498

NCBI Accession: NP_000370

Pathways: Positive Regulation of Endopeptidase Activity