MANF anticorps
Aperçu rapide pour MANF anticorps (ABIN956418)
Antigène
Voir toutes MANF AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Human MANF
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Purification
- IgG fraction purifiedwith Protein G affinity chromatorgaphy
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Immunogène
- Recombinant human MANF protein produced using CHO-basedIcosagen Cell factory Ltd. proprietary suspension cell line. Immunogen is purifiedfrom cell culture supernatant
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Isotype
- IgG1
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Indications d'application
- ELISA1:32 000, Western immunoblotting 1:2000 – 1:4000. Monoclonal antibody working titer has to be established practically for each particular antigen and assay format
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Commentaires
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Synonym: ARMET, ARP
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/ml
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Buffer
- PBS pH 7.4, with 0.1%
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- This product is shipped in non-frozen liquid form in ambient conditions
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- MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
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Autre désignation
- MANF
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Sujet
- MANF is a trophic factor for midbrain dopamine neuronsin vivo. It prevents the 6-OHDA-induced degeneration of dopamine neurons in rodent models of Parkinson’sdisease (Lindholm et al., 2008, Voutilainen et al., 2009). When administeredafter 6-OHDA-lesioning it restores the dopaminergic function and prevents degenerationof dopamine neurons in substantia nigra pars compacta
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UniProt
- P55145
Antigène
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