UNG anticorps (AA 281-298)

N° du produit ABIN959421

Cet anticorps anti-UNG est un anticorps Lapin Polyclonal détectant UNG dans WB, IHC et IHC (p). Adapté pour Humain.

Aperçu rapide pour UNG anticorps (AA 281-298) (ABIN959421)

Antigène: UNG (Uracil-DNA Glycosylase (UNG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNG est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-UNG anticorps

Épitope: AA 281-298

Marque: IHC-plus™

Specificité: The synthetic peptide sequence used for immunogen is 100 % conserved between UNG1 and UNG2. Thus recognizes both UNG1 and UNG2. As UNG1 and UNG2 are not resolved as two species in gel electrophoresis (Huag et al., 1998), they are indistinguishable by western blot. The observed molecular weight of UNG (UNG1 and UNG2) on western blots may vary: 26 kD, 27.5 kD, 31 kD, and 38 kD forms have been described (Bharati et al., 1998, Slupphaug et al., 1993). Please see Kruman et al. (Fig. 1D, 2004) for an example of western blot in rat. This specificity of this has been validated by antisense UNG oligonucleotide (Kruman et al. 2004).

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%) Gibbon, Marmoset, Mouse, Dog, Bat, Bovine, Horse, Rabbit, Turkey, Chicken (94%) Rat, Hamster, Elephant, Panda, Pig, Platypus (89%) Zebrafish (83%).

Purification: Protein G purified

Immunogène: Synthetic peptide sequence CRHFSKTNELLQKSGKKP corresponding to amino acids 281-298 of human UNG1 (NP003353.1) and amino acids 290-307 of human UNG2 (NP 550433.1). The peptide sequence used for immunogen is highly conserved between mammalian and invertabrates. Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%), Gibbon, Marmoset, Mouse, Dog, Bat, Bovine, Horse, Rabbit, Turkey, Chicken (94%), Rat, Hamster, Elephant, Panda, Pig, Platypus (89%), Zebrafish (83%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Information d'application

Indications d'application: Approved: IHC, IHC-P (10 μg/mL), WB (2 μg/mL)

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS containing 0.05 % BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur UNG

Antigène: UNG (Uracil-DNA Glycosylase (UNG))

Autre désignation: UNG / Uracil DNA Glycosylase

Sujet: Name/Gene ID: UNG

Synonyms: UNG, DGU, HIGM4, HIGM5, Uracil-DNA glycosylase, UNG1, UNG2, UDG, UNG15

ID gène: 7374

UniProt: P13051

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response