PRDM1 anticorps (C-Term)

N° du produit ABIN964913

Détail du produit anti-PRDM1 anticorps

Antigène: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRDM1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: This affinity purified antibody is directed against human BLIMP1 protein. The product was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is predicted to react with BLIMP1 and its isoforms from human, mouse, rat and other sources based on a 100% homology with the immunizing sequence. This antibody may also recognize other proteins that show high homology/identity with the BLIMP1 sequence.

Réactivité croisée: Souris, Rat (Rattus), Chien

Attributs du produit: PRDM1/Blimp1 (PR domain zinc finger protein 1, PR domain-containing protein 1, Beta-interferon gene positive regulatory domain I-binding factor, BLIMP-1, Positive regulatory domain I-binding factor 1, PRDI-binding factor 1, or PRDI-BF1, or Beta-lymphocyte-induced maturation protein 1) is one of several transcription factors which drives the maturation of B-lymphocytes into Ig secreting cells. In the nucleus, PRDM1/BLIMP1 functions as a transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Transcription of the PRDM1 gene is increased upon virus induction. PRDM1/Blimp1 also interacts with PRMT5. Two alternatively spliced transcript variants that encode different isoforms have been reported.

Purification: affinity purified

Stérilité: Sterile filtered

Immunogène: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the C-terminus of human, mouse, and rat PRDM1/BLIMP1.
Immunogen Type: Peptide

Isotype: IgG

Information d'application

Indications d'application: This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band at ~88 kDa in size corresponding to BLIMP1 by western blotting in the appropriate cell lysate or extract.

Commentaires:

Gene Name: PRDM1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.15 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Date de péremption: 12 months

Détails sur PRDM1

Antigène: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Autre désignation: PRDM1 BLIMP1 (PRDM1 Produits)

Synonymes: anticorps GB11750, anticorps CG5249, anticorps Dmel\\CG5249, anticorps blimp-1, anticorps dBlimp-1, anticorps dBlimp1, anticorps Blimp-1, anticorps Blimp1, anticorps nrd, anticorps prdm1, anticorps ubo, anticorps wu:fb99c12, anticorps zgc:91885, anticorps MGC52536, anticorps PRDM1, anticorps blimp1, anticorps xblimp1, anticorps prdi-bf1, anticorps BLIMP1, anticorps PRDI-BF1, anticorps ZNFPR1A1, anticorps PR/SET domain 1, anticorps probable serine/threonine-protein kinase DDB_G0282963, anticorps CG5249 gene product from transcript CG5249-RF, anticorps blimp-1, anticorps PR domain containing 1a, with ZNF domain, anticorps PR domain 1 S homeolog, anticorps B lymphocyte induced maturation protein 1, anticorps PR domain 1, anticorps PR domain containing 1, with ZNF domain, anticorps PRDM1, anticorps LOC408295, anticorps Blimp-1, anticorps CpipJ_CPIJ007425, anticorps prdm1a, anticorps prdm1.S, anticorps prdm1, anticorps Prdm1

Sujet: PRDM1/Blimp1 (PR domain zinc finger protein 1, PR domain-containing protein 1, Beta-interferon gene positive regulatory domain I-binding factor, BLIMP-1, Positive regulatory domain I-binding factor 1, PRDI-binding factor 1, or PRDI-BF1, or Beta-lymphocyte-induced maturation protein 1) is one of several transcription factors which drives the maturation of B-lymphocytes into Ig secreting cells. In the nucleus, PRDM1/BLIMP1 functions as a transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Transcription of the PRDM1 gene is increased upon virus induction. PRDM1/Blimp1 also interacts with PRMT5. Two alternatively spliced transcript variants that encode different isoforms have been reported.
Synonyms: PR domain zinc finger protein 1, PR domain-containing protein 1, Beta-interferon gene positive regulatory domain I-binding factor, BLIMP-1, Beta-lymphocyte-induced maturation protein 1

ID gène: 639, 25008939

UniProt: Q60636

Pathways: Regulation of Muscle Cell Differentiation