PLAP anticorps

N° du produit ABIN965542

Cet anticorps Souris Monoclonal détecte spécifiquement PLAP dans WB, IHC et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour PLAP anticorps (ABIN965542)

Antigène: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PLAP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 3E5

Détail du produit anti-PLAP anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human ALPP expressed in E. Coli.

Isotype: IgG2b

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-PLAP (ABIN965542)

Llinas, Stura, Ménez, Kiss, Stigbrand, Millán, Le Du: "Structural studies of human placental alkaline phosphatase in complex with functional ligands." dans: Journal of molecular biology, Vol. 350, Issue 3, pp. 441-51, (2005) (PubMed).

Chen, Anderson, Hiroi, Medof: "Proprotein interaction with the GPI transamidase." dans: Journal of cellular biochemistry, Vol. 88, Issue 5, pp. 1025-37, (2003) (PubMed).

Détails sur PLAP

Antigène: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Autre désignation: ALPP

Sujet: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placentallike form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
Synonyms: ALP, PALP, PLAP, FLJ61142, ALPP

Poids moléculaire: 58kDa

ID gène: 250