BNP anticorps

N° du produit ABIN965690

Il existe 2+ publications pour ce produit. L’anticorps anti-BNP Monoclonal Souris est utilisé pour la détection de BNP dans des échantillons de Humain. Il a été validé pour IHC et ELISA.

Aperçu rapide pour BNP anticorps (ABIN965690)

Antigène: BNP (Brain Natriuretic Peptide (BNP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BNP est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Clone: 9H6B4-9H6H4A7

Détail du produit anti-BNP anticorps

Purification: Ascitic fluid

Immunogène: Synthetic peptide corresponding to aa (Gly-Leu-Gln-Glu-Gln-Arg-Asn-His-Leu-Gln-Gly-Lys-Leu-Cys) of human BNP, conjugated to KLH.

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-BNP (ABIN965690)

Pfister, Erdmann, Schneider: "[Natriuretic peptides BNP and NT-pro-BNP--the "new troponins" for estimation of heart failure?]." dans: Deutsche medizinische Wochenschrift (1946), Vol. 128, Issue 18, pp. 1007-12, (2003) (PubMed).

Dawson, Struthers: "Screening for treatable left ventricular abnormalities in diabetic patients." dans: Expert opinion on biological therapy, Vol. 3, Issue 1, pp. 107-12, (2003) (PubMed).

Détails sur BNP

Antigène: BNP (Brain Natriuretic Peptide (BNP))

Autre désignation: BNP

Sujet: BNP (brain natriuretic peptide) belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. BNP circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. It is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic.
Synonyms: BNP, NPPB

ID gène: 4879

Pathways: Hormone Activity