MME anticorps

N° du produit ABIN965758

Cet anticorps Monoclonal détecte spécifiquement MME dans IHC et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour MME anticorps (ABIN965758)

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp MME est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-MME anticorps

Specificité: Ni-NTA purified recombinant human CD-10 expressed in E. Coli strain BL21 (DE3).

Purification: Antibodies are purified by protein G affinity chromatography.

Isotype: IgG2b

Information d'application

Indications d'application: IHC(P): Dilution 1: 100- 1: 200
IHC(F): Dilution 1: 200- 1: 400
ELISA: Propose dilution 1: 10000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Stock: -20 °C

Références pour anticorps anti-MME (ABIN965758)

Sato, Itoh, Hinoda, Ohe, Nakagawa, Ueda, Yachi, Imai: "Expression of CD10/neutral endopeptidase in normal and malignant tissues of the human stomach and colon." dans: Journal of gastroenterology, Vol. 31, Issue 1, pp. 12-7, (1996) (PubMed).

Inukai, Sugita, Iijima, Tezuka, Goi, Kojika, Shiraishi, Kagami, Nakazawa: "Expression of granulocyte colony-stimulating factor receptor on CD10-positive human B-cell precursors." dans: British journal of haematology, Vol. 89, Issue 3, pp. 623-6, (1995) (PubMed).

Détails sur MME

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Autre désignation: CD10

Classe de substances: Chemical

Sujet: CD10 is a 100kDa glycoprotein, also designated Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

ID gène: 4311

Pathways: Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration