CD31 anticorps

N° du produit ABIN965785

Cet anticorps Monoclonal détecte spécifiquement CD31 dans WB, IHC et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour CD31 anticorps (ABIN965785)

Antigène: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp CD31 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-CD31 anticorps

Specificité: Ni-NTA purified recombinant CD31 expressed in E. Coli strain BL21 (DE3)

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Stock: -20 °C

Références pour anticorps anti-CD31 (ABIN965785)

Mayr, Zou, Zhang, Dietrich, Hu, Xu: "Accelerated arteriosclerosis of vein grafts in inducible NO synthase(-/-) mice is related to decreased endothelial progenitor cell repair." dans: Circulation research, Vol. 98, Issue 3, pp. 412-20, (2006) (PubMed).

Bingle, Lewis, Corke, Reed, Brown: "Macrophages promote angiogenesis in human breast tumour spheroids in vivo." dans: British journal of cancer, Vol. 94, Issue 1, pp. 101-7, (2006) (PubMed).

Wynne, Ball, McLellan, Dockery, Zimmermann, Moore: "Mouse pregnancy-specific glycoproteins: tissue-specific expression and evidence of association with maternal vasculature." dans: Reproduction (Cambridge, England), Vol. 131, Issue 4, pp. 721-32, (2006) (PubMed).

Détails sur CD31

Antigène: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Autre désignation: CD31

Sujet: CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors.It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. The antibody reacts with the murine form of the Platelet-Endothelial Cell Adhesion Molecule. The reactivity of the antibody is restricted to the isoform of the molecule that is selectively expressed by endothelial cells.The antigen is predominantly present at the lateral borders of endothelial cells as described for human PECAM-1.It is also weakly expressed on many peripheral lymphoid cells and platelets. CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).

ID gène: 5175

Pathways: Regulation of Actin Filament Polymerization