CD8 alpha anticorps

N° du produit ABIN965822

Détail du produit anti-CD8 alpha anticorps

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD8 alpha est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Acetone-fixed) (IHC (af))

Specificité: This antibody consists of a disufide-linked / hetrodimer with a mW of 30 kD or an / homodimer with a MW of 32 kD. The CD molecule binds to HLA class I molecule during interaction of CD 8+ T cells with antigenpresenting cells or with target cells. CD 8+T cells include most of the cytotoxic T cells.

Attributs du produit: This antibody is directed against alpha chain of CD8 molecule.

Purification: Purified.

Clone: B441 (143-44 )

Isotype: IgG kappa

Information d'application

Indications d'application: Flow: not tested in our lab.
IHC (acetone-fixed frozen).
Staining Procedure: Acetone-fixed tissue sections at 1:50-1:100 Antibody

Commentaires:

Cellular Localization: Cell membrane.
Recommended Positive Control: Human peripheral lymphocytes, Human tonsil.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/0.5 ml.

Buffer: Protein A/G purified, 0.2 mg in 50 mM Borate, 150mM NaCl, 20 % Glycerol, pH 8.0

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-CD8 alpha (ABIN965822)

Akimoto, Kaneko, Sekigawa, Hashimoto, Kaneko, Yamamoto: "Binding of HIV-2 envelope glycoprotein to CD8 molecules and related chemokine production." dans: Immunology, Vol. 95, Issue 2, pp. 214-8, (1999) (PubMed).

Washizuka, Aizawa, Chinushi, Naitoh, Miyajima, Kusano, Kitazawa, Uchiyama, Takahashi, Shibata: "Alternation of QRS morphology and effect of radiofrequency ablation in idiopathic ventricular tachycardia." dans: Pacing and clinical electrophysiology : PACE, Vol. 18, Issue 1 Pt 1, pp. 18-27, (1995) (PubMed).

Détails sur CD8 alpha

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Autre désignation: CD8a (CD8A Produits)

Synonymes: anticorps cd8, anticorps LOC100136450, anticorps BB154331, anticorps Ly-2, anticorps Ly-35, anticorps Ly-B, anticorps Lyt-2, anticorps zgc:136643, anticorps CD8, anticorps Leu2, anticorps MAL, anticorps p32, anticorps RHACD8-4, anticorps CD8a molecule, anticorps uncharacterized LOC100125537, anticorps CD8 alpha, anticorps CD8 antigen, alpha chain, anticorps T-cell surface glycoprotein CD8 alpha chain, anticorps Cd8a, anticorps LOC100125537, anticorps LOC100136450, anticorps CD8A, anticorps cd8a, anticorps LOC100126556

Poids moléculaire: 32 kDa

ID gène: 925

Pathways: TCR Signaling