CDK2 anticorps

N° du produit ABIN965843

4+ publications sont disponibles pour ce produit. L’anticorps anti-CDK2 Polyclonal produit chez le Lapin a été validé pour IHC. Il convient pour la détection de CDK2 dans des échantillons provenant de Humain, Souris et Rat. }

Aperçu rapide pour CDK2 anticorps (ABIN965843)

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK2 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-CDK2 anticorps

Specificité: CDK2 (Ab-160) antibody detects endogenous levels of total CDK2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human CDK2 around the phosphorylation site of threonine160 (T-Y-TP-H-E).

Information d'application

Indications d'application: WB: 1:500~1:1000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-CDK2 (ABIN965843)

Liu, Wu, Galaktionov: "p42, a novel cyclin-dependent kinase-activating kinase in mammalian cells." dans: The Journal of biological chemistry, Vol. 279, Issue 6, pp. 4507-14, (2004) (PubMed).

Ukomadu, Dutta: "Inhibition of cdk2 activating phosphorylation by mevastatin." dans: The Journal of biological chemistry, Vol. 278, Issue 7, pp. 4840-6, (2003) (PubMed).

Morris, Gondeau, Tainer, Divita: "Kinetic mechanism of activation of the Cdk2/cyclin A complex. Key role of the C-lobe of the Cdk." dans: The Journal of biological chemistry, Vol. 277, Issue 26, pp. 23847-53, (2002) (PubMed).

Brown, Noble, Lawrie, Morris, Tunnah, Divita, Johnson, Endicott: "Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity." dans: The Journal of biological chemistry, Vol. 274, Issue 13, pp. 8746-56, (1999) (PubMed).

Détails sur CDK2

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Autre désignation: CDK2

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA