GJB1 anticorps (AA 215-231)

N° du produit ABIN965915

L’anticorps Polyclonal anti-GJB1 a été validé pour WB et IHC (p). Il convient pour détecter GJB1 dans des échantillons de Humain et Rat. Il y a 2+ publications disponibles.

Aperçu rapide pour GJB1 anticorps (AA 215-231) (ABIN965915)

Antigène: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Reactivité: Humain, Rat

Hôte: Veuillez nous consulter SVP

Clonalité: Polyclonal

Conjugué: Cet anticorp GJB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GJB1 anticorps

Épitope: AA 215-231

Immunogène: A synthetic peptide corresponding to a sequence at the middle region of human Connexin 32 (215-231aa), identical to the related mouse and rat sequence.

Information d'application

Restrictions: For Research Use only

Stockage

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Stock: -20 °C

Références pour anticorps anti-GJB1 (ABIN965915)

Hoek, Schlegel, Eichhoff, Widmer, Praetorius, Einarsson, Valgeirsdottir, Bergsteinsdottir, Schepsky, Dummer, Steingrimsson: "Novel MITF targets identified using a two-step DNA microarray strategy." dans: Pigment cell & melanoma research, Vol. 21, Issue 6, pp. 665-76, (2008) (PubMed).

Corcos, Lafrenière, Begy, Loch-Caruso, Willard, Glover: "Refined localization of human connexin32 gene locus, GJB1, to Xq13.1." dans: Genomics, Vol. 13, Issue 2, pp. 479-80, (1992) (PubMed).

Détails sur GJB1

Antigène: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Autre désignation: Connexin 32

Sujet: Connexins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells (Bergoffen et al., 1993). For a general discussion of connexin proteins, also known as Gap junction beta-1 protein. Gap junction beta-1 protein is a protein that in humans is encoded by the GJB1 gene.In melanocytic cells GJB1 gene expression may be regulated by MITF.

Pathways: Cell-Cell Junction Organization