Cytokeratin 5 anticorps

N° du produit ABIN965961

Cet anticorps anti-Cytokeratin 5 est un anticorps Souris Monoclonal détectant Cytokeratin 5 dans WB et ELISA. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour Cytokeratin 5 anticorps (ABIN965961)

Antigène: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cytokeratin 5 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 3E2F1

Détail du produit anti-Cytokeratin 5 anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of CK5 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-Cytokeratin 5 (ABIN965961)

Leibl, Moinfar: "Mammary NOS-type sarcoma with CD10 expression: a rare entity with features of myoepithelial differentiation." dans: The American journal of surgical pathology, Vol. 30, Issue 4, pp. 450-6, (2006) (PubMed).

Détails sur Cytokeratin 5

Antigène: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Autre désignation: Cytokeratin 5

Sujet: CK5 (keratin 5) is a member of the keratin gene family. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin5 gene (KRT5) have been shown to result in the autosomal dominant disorderepidermolysis bullosa (EB). Defects in KRT5 are a cause of epidermolysis bullosa simplex.
Synonyms: K5, DDD, EBS2, KRT5A, KRT5

ID gène: 3852