Purified by antigen-specific affinity chromatography.
Immunogène
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse DAPK3(Death-associated protein kinase 3)
anticorps DAPK3, anticorps dapk3, anticorps wu:fc25b08, anticorps si:dkey-57k2.5, anticorps MGC114871, anticorps ZIP, anticorps ZIPK, anticorps dlk, anticorps Dapkl, anticorps death associated protein kinase 3, anticorps death-associated protein kinase 3, anticorps death-associated protein kinase 3 L homeolog, anticorps DAPK3, anticorps dapk3, anticorps dapk3.L, anticorps Dapk3
Sujet
DAPK3(Death-associated protein kinase 3) belongs to the Ser/Thr protein kinase family which acts as a positive regulator of apoptosis. DAPK3 is a homodimer or forms heterodimers with ATF4. Both interactions require an intact leucine zipper domain and oligomerization is required for full enzymatic activity. It also binds to DAXX and PAWR, possibly in a ternary complex which plays a role in caspase activation.