Dynamin 1 anticorps

N° du produit ABIN966017

L’anticorps Monoclonal anti-Dynamin 1 a été validé pour WB, ELISA et IHC. Il convient pour détecter Dynamin 1 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour Dynamin 1 anticorps (ABIN966017)

Antigène: Dynamin 1 (DNM1)

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp Dynamin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Dynamin 1 anticorps

Specificité: Ni-NTA purified truncated recombinant Dynamin-1 expressed in E. Coli strain BL21 (DE3)

Purification: Crude ascites.

Isotype: IgG2a

Information d'application

Indications d'application: Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000 Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: -20 °C

Références pour anticorps anti-Dynamin 1 (ABIN966017)

Yoo, Jeong, Kwon, Hur, Park, Han: "Activation of dynamin I gene expression by Sp1 and Sp3 is required for neuronal differentiation of N1E-115 cells." dans: The Journal of biological chemistry, Vol. 277, Issue 14, pp. 11904-9, (2002) (PubMed).

Détails sur Dynamin 1

Antigène: Dynamin 1 (DNM1)

Autre désignation: Dynamin-1

Sujet: Dynamin-1 (Dyn1), with 864-amino acid protein (about 95kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation.

Pathways: Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling