Estrogen Receptor alpha anticorps

N° du produit ABIN966104

Il existe 3+ publications pour ce produit. L’anticorps anti-Estrogen Receptor alpha Polyclonal Lapin est utilisé pour la détection de Estrogen Receptor alpha dans des échantillons de Humain et Souris. Il a été validé pour IHC.

Aperçu rapide pour Estrogen Receptor alpha anticorps (ABIN966104)

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Estrogen Receptor alpha est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-Estrogen Receptor alpha anticorps

Specificité: Estrogen Receptor- (Ab-118) antibody detects endogenous levels of total Estrogen Receptor- protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human Estrogen Receptor- around the phosphorylation site of serine118 (Q-L-SP-P-F).

Information d'application

Indications d'application: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-Estrogen Receptor alpha (ABIN966104)

Pentecost, Bradley, Gierthy, Ding, Fasco: "Gene regulation in an MCF-7 cell line that naturally expresses an estrogen receptor unable to directly bind DNA." dans: Molecular and cellular endocrinology, Vol. 238, Issue 1-2, pp. 9-25, (2005) (PubMed).

Medunjanin, Hermani, De Servi, Grisouard, Rincke, Mayer: "Glycogen synthase kinase-3 interacts with and phosphorylates estrogen receptor alpha and is involved in the regulation of receptor activity." dans: The Journal of biological chemistry, Vol. 280, Issue 38, pp. 33006-14, (2005) (PubMed).

Masuhiro, Mezaki, Sakari, Takeyama, Yoshida, Inoue, Yanagisawa, Hanazawa, Omalley, Kato: "Splicing potentiation by growth factor signals via estrogen receptor phosphorylation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 23, pp. 8126-31, (2005) (PubMed).

Détails sur Estrogen Receptor alpha

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Autre désignation: Estrogen Receptor-alpha

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly