FANCG anticorps (C-Term)

N° du produit ABIN966129

Cet anticorps anti-FANCG est un anticorps Lapin Polyclonal détectant FANCG dans IHC. Adapté pour Humain. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour FANCG anticorps (C-Term) (ABIN966129)

Antigène: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FANCG est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-FANCG anticorps

Épitope: C-Term

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human FANCG (Fanconi anemia group G protein)

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Références pour anticorps anti-FANCG (ABIN966129)

Meetei, Levitus, Xue, Medhurst, Zwaan, Ling, Rooimans, Bier, Hoatlin, Pals, de Winter, Wang, Joenje: "X-linked inheritance of Fanconi anemia complementation group B." dans: Nature genetics, Vol. 36, Issue 11, pp. 1219-24, (2004) (PubMed).

Demuth, Wlodarski, Tipping, Morgan, de Winter, Thiel, Gräsl, Schindler, DAndrea, Altay, Kayserili, Zatterale, Kunze, Ebell, Mathew, Joenje, Sperling, Digweed: "Spectrum of mutations in the Fanconi anaemia group G gene, FANCG/XRCC9." dans: European journal of human genetics : EJHG, Vol. 8, Issue 11, pp. 861-8, (2000) (PubMed).

Garcia-Higuera, Kuang, Näf, Wasik, DAndrea: "Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex." dans: Molecular and cellular biology, Vol. 19, Issue 7, pp. 4866-73, (1999) (PubMed).

Détails sur FANCG

Antigène: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Autre désignation: FANCG

Sujet: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. FANCG may be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. FANCG is a andidate tumor suppressor gene. FANCG belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. The complex is not found in FA patients. The major form is nuclear. The minor form is cytoplasmic. Highly expressed in testis and thymus. Found in lymphoblasts. Defects in FANCG are a cause of Fanconi anemia (FA)
Synonym: XRCC9 (DNA repair protein XRCC9)

Pathways: Réparation de l'ADN