Fibulin 5 anticorps

N° du produit ABIN966144

Cet anticorps anti-Fibulin 5 est un anticorps Monoclonal détectant Fibulin 5 dans WB et ELISA. Adapté pour Humain. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour Fibulin 5 anticorps (ABIN966144)

Antigène: Fibulin 5 (FBLN5)

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp Fibulin 5 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Fibulin 5 anticorps

Specificité: Ni-NTA purified truncated recombinant Fibulin 5 expressed in E. Coli strain BL21 (DE3)

Purification: Crude ascites.

Isotype: IgM

Information d'application

Indications d'application: Western Blot: 1: 500- 1: 2000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: -20 °C

Références pour anticorps anti-Fibulin 5 (ABIN966144)

Wen, Hochholdinger, Sauer, Bruce, Schnable: "The roothairless1 gene of maize encodes a homolog of sec3, which is involved in polar exocytosis." dans: Plant physiology, Vol. 138, Issue 3, pp. 1637-43, (2005) (PubMed).

Kadoya, Sasaki, Kostka, Timpl, Matsuzaki, Kumagai, Sakai, Nishiyama, Amano: "Fibulin-5 deposition in human skin: decrease with ageing and ultraviolet B exposure and increase in solar elastosis." dans: The British journal of dermatology, Vol. 153, Issue 3, pp. 607-12, (2005) (PubMed).

Lee, Roy, Mogford, Schiemann, Mustoe: "Fibulin-5 promotes wound healing in vivo." dans: Journal of the American College of Surgeons, Vol. 199, Issue 3, pp. 403-10, (2004) (PubMed).

Détails sur Fibulin 5

Antigène: Fibulin 5 (FBLN5)

Autre désignation: Fibulin 5

Sujet: Fibulin 5(FBLN5), with 448-amino acid protein (about 50kDa), is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.

Pathways: SARS-CoV-2 Protein Interactome