EHMT1 anticorps

N° du produit ABIN966204

Détail du produit anti-EHMT1 anticorps

Antigène: EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp EHMT1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Ni-NTA purified truncated recombinant GLP expressed in E. Coli strain BL21 (DE3)

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: Dilution 1: 200- 1: 1,000
ELISA: Propose dilution 1: 10,000
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Stock: -20 °C

Références pour anticorps anti-EHMT1 (ABIN966204)

Young: "Inhibition of glucagon secretion." dans: Advances in pharmacology (San Diego, Calif.), Vol. 52, pp. 151-71, (2006) (PubMed).

De León, Crutchlow, Ham, Stoffers: "Role of glucagon-like peptide-1 in the pathogenesis and treatment of diabetes mellitus." dans: The international journal of biochemistry & cell biology, Vol. 38, Issue 5-6, pp. 845-59, (2006) (PubMed).

Détails sur EHMT1

Antigène: EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))

Autre désignation: GLP (EHMT1 Produits)

Synonymes: anticorps EUHMTASE1, anticorps Eu-HMTase1, anticorps FP13812, anticorps GLP, anticorps GLP1, anticorps KMT1D, anticorps bA188C12.1, anticorps EHMT1, anticorps G9a, anticorps 9230102N17Rik, anticorps D330003E03, anticorps mKIAA1876, anticorps bZ1O1.6, anticorps si:rp71-1o1.6, anticorps zgc:136244, anticorps euchromatic histone lysine methyltransferase 1, anticorps histone-lysine N-methyltransferase EHMT2, anticorps euchromatic histone-lysine N-methyltransferase 1, anticorps euchromatic histone methyltransferase 1, anticorps euchromatic histone-lysine N-methyltransferase 1a, anticorps EHMT1, anticorps Ehmt1, anticorps LOC100121084, anticorps ehmt1, anticorps ehmt1a

Sujet: Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L cells in response to ingested nutrients. The closely related peptides glucagon-like peptide (GLP-1) and glucagon have opposing effects on blood glucose. GLP-1 induces glucose-dependent insulin secretion in the pancreas, while glucagon stimulates gluconeogenesis and glycogenolysis in the liver. Glucagon is processed from a large precursor, proglucagon, in a tissue-specific manner in pancreatic alpha-cells. The identification of a hybrid peptide acting as both a GLP-1 agonist and a glucagon antagonist would provide a novel approach for the treatment of type 2 diabetes.

ID gène: 79813