EHMT1 anticorps

N° du produit ABIN969480

Cité dans 2 publications. Cet anticorps anti-EHMT1 Monoclonal Souris (Clone 1B7B4) (ABIN969480) détecte spécifiquement EHMT1 dans ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour EHMT1 anticorps (ABIN969480)

Antigène: EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EHMT1 est non-conjugé

Application: ELISA

Clone: 1B7B4

Détail du produit anti-EHMT1 anticorps

Fonction: GLP Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of GLP expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-EHMT1 (ABIN969480)

De León, Crutchlow, Ham, Stoffers: "Role of glucagon-like peptide-1 in the pathogenesis and treatment of diabetes mellitus." dans: The international journal of biochemistry & cell biology, Vol. 38, Issue 5-6, pp. 845-59, (2006) (PubMed).

Young: "Inhibition of glucagon secretion." dans: Advances in pharmacology (San Diego, Calif.), Vol. 52, pp. 151-71, (2006) (PubMed).

Détails sur EHMT1

Antigène: EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))

Autre désignation: GLP

Sujet: Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L cells in response to ingested nutrients. The closely related peptides glucagon-like peptide (GLP-1) and glucagon have opposing effects on blood glucose. GLP-1 induces glucose-dependent insulin secretion in the pancreas, while glucagon stimulates gluconeogenesis and glycogenolysis in the liver. Glucagon is processed from a large precursor, proglucagon, in a tissue-specific manner in pancreatic alpha-cells. The identification of a hybrid peptide acting as both a GLP-1 agonist and a glucagon antagonist would provide a novel approach for the treatment of type 2 diabetes.

ID gène: 79813

UniProt: Q9H9B1