IL1A anticorps

N° du produit ABIN966392

Il existe 1 publication pour ce produit. L’anticorps anti-IL1A Monoclonal est utilisé pour la détection de IL1A dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour IL1A anticorps (ABIN966392)

Antigène: IL1A (Interleukin 1 alpha (IL1A))

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp IL1A est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-IL1A anticorps

Specificité: Ni-NTA purified recombinant human IL-1 alpha, expressed in E. Coli strain BL21 (DE3).

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG2a

Information d'application

Indications d'application: Dilution: Western Blot: 1:500-1,000
ELISA: Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Stock: -20 °C

Références pour anticorps anti-IL1A (ABIN966392)

Du, Dodel, Eastwood, Bales, Gao, Lohmüller, Müller, Kurz, Zimmer, Evans, Hake, Gasser, Oertel, Griffin, Paul, Farlow: "Association of an interleukin 1 alpha polymorphism with Alzheimer's disease." dans: Neurology, Vol. 55, Issue 4, pp. 480-3, (2000) (PubMed).

Détails sur IL1A

Antigène: IL1A (Interleukin 1 alpha (IL1A))

Autre désignation: IL-1a

Sujet: Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

ID gène: 3552

Pathways: Signalisation NF-kappaB, Autophagy, Cancer Immune Checkpoints