ITK anticorps (AA 2-110)

N° du produit ABIN966422

Il existe 2+ publications pour ce produit. L’anticorps anti-ITK Monoclonal Souris est utilisé pour la détection de ITK dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour ITK anticorps (AA 2-110) (ABIN966422)

Antigène: ITK (IL2-Inducible T-Cell Kinase (ITK))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITK est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 5G12C4

Détail du produit anti-ITK anticorps

Épitope: AA 2-110

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of ITK (aa2-110) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-ITK (ABIN966422)

Graves, Siroux, Guerra, Klimecki, Martinez: "Association of atopy and eczema with polymorphisms in T-cell immunoglobulin domain and mucin domain-IL-2-inducible T-cell kinase gene cluster in chromosome 5 q 33." dans: The Journal of allergy and clinical immunology, Vol. 116, Issue 3, pp. 650-6, (2005) (PubMed).

Perez-Villar, ODay, Hewgill, Nadler, Kanner: "Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin alpha (Rch1alpha)." dans: International immunology, Vol. 13, Issue 10, pp. 1265-74, (2001) (PubMed).

Détails sur ITK

Antigène: ITK (IL2-Inducible T-Cell Kinase (ITK))

Autre désignation: ITK

Sujet: ITK: IL2-inducible T-cell kinase. This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.
Synonyms: EMT, LYK, PSCTK2

ID gène: 3702

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway