LIM Domain Kinase 1 anticorps

N° du produit ABIN966485

L’anticorps Lapin Polyclonal anti-LIM Domain Kinase 1 a été validé pour IHC. Il convient pour détecter LIM Domain Kinase 1 dans des échantillons de Humain, Souris et Rat. Il y a 3+ publications disponibles.

Aperçu rapide pour LIM Domain Kinase 1 anticorps (ABIN966485)

Antigène: LIM Domain Kinase 1 (LIMK1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIM Domain Kinase 1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-LIM Domain Kinase 1 anticorps

Specificité: LIMK1 (Ab-508) antibody detects endogenous levels of total LIMK1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human LIMK1 around the phosphorylation site of threonine 508 (R-Y-TP-V-V).

Information d'application

Indications d'application: WB: 1:500~1:1000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-LIM Domain Kinase 1 (ABIN966485)

Soosairajah, Maiti, Wiggan, Sarmiere, Moussi, Sarcevic, Sampath, Bamburg, Bernard: "Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin." dans: The EMBO journal, Vol. 24, Issue 3, pp. 473-86, (2005) (PubMed).

Ohashi, Nagata, Maekawa, Ishizaki, Narumiya, Mizuno: "Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop." dans: The Journal of biological chemistry, Vol. 275, Issue 5, pp. 3577-82, (2000) (PubMed).

Edwards, Sanders, Bokoch, Gill: "Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics." dans: Nature cell biology, Vol. 1, Issue 5, pp. 253-9, (1999) (PubMed).

Détails sur LIM Domain Kinase 1

Antigène: LIM Domain Kinase 1 (LIMK1)

Autre désignation: LIMK1

Pathways: Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events