Lipoprotein Lipase anticorps
Aperçu rapide pour Lipoprotein Lipase anticorps (ABIN966491)
Antigène
Voir toutes Lipoprotein Lipase (LPL) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Human LPL whole protein. Recognizes specifically LPL from human and bovine.
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Isotype
- IgG1
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Indications d'application
- Western blot (1:1000) and ELISA (1:2000~5000) in lipid metabolic research.
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Restrictions
- For Research Use only
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Concentration
- 1mg/ml
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Buffer
- PBS, pH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- Lipoprotein Lipase (LPL)
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Autre désignation
- LPL
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Sujet
- Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promote the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF ) secretion and induction of vascular smooth muscle cell proliferation.
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ID gène
- 4023
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Pathways
- Lipid Metabolism
Antigène
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