LSD1 anticorps

N° du produit ABIN966497

L’anticorps Monoclonal anti-LSD1 a été validé pour WB, ELISA et IHC. Il convient pour détecter LSD1 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour LSD1 anticorps (ABIN966497)

Antigène: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp LSD1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-LSD1 anticorps

Specificité: Ni-NTA purified truncated recombinant human LSD1 expressed in E. Coli strain BL21 (DE3)

Purification: Crude Asites are purified by protein A affinity chromatography.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Stock: -20 °C

Références pour anticorps anti-LSD1 (ABIN966497)

Metzger, Wissmann, Yin, Müller, Schneider, Peters, Günther, Buettner, Schüle: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." dans: Nature, Vol. 437, Issue 7057, pp. 436-9, (2005) (PubMed).

Détails sur LSD1

Antigène: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Autre désignation: LSD1/AOF2

Sujet: The amine oxidase domain 2(AOF2)gene encodes a nuclear protein(LSD1,~95kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex(es) on chromatin.

ID gène: 23028

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, L'effet Warburg