NOX3 anticorps (NADPH Oxidase 3) (C-Term)

Details for Product anti-NOX3 Antibody No. ABIN966688, Fournisseur: Connectez-vous pour afficher
Antigène
  • GP91-3
  • het
  • nmf250
  • MOX-2
  • NADPH oxidase 3
  • Nox3
  • NOX3
  • nox3
Épitope
C-Term
11
10
7
5
3
2
2
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
64
46
27
Hôte
Lapin
67
Clonalité
Polyclonal
Conjugué
Cet anticorp NOX3 est non-conjugé
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
47
42
19
13
9
4
2
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human NOX3(NADPH oxidase 3)
Plasmids, Primers & others Plasmids, Primers & others NOX3 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation NOX3 (NOX3 Antibody Extrait)
Sujet NADPH oxidase which constitutively produces superoxide upon formation of a complex with CYBA/p22phox. NOX3(NADPH oxidase 3) plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. NOX3(NADPH oxidase 3) is activated by the ototoxic drug cisplatin and by NOXO1. NOX3 is cooperatively activated by NCF1 and NCF2 or NOXA1 in a phorbol 12-myristate 13-acetate (PMA)-dependent manner. It is inhibited by diphenyleneiodonium chloride and interacts with and stabilizes CYBA/p22phox. NOX3 is expressed in fetal kidney and to a lower extent in liver, lung and spleen.
Synonyms: MOX2
Restrictions For Research Use only
Produit citée dans: Ueno, Takeya, Miyano, Kikuchi, Sumimoto: "The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators." dans: The Journal of biological chemistry, Vol. 280, Issue 24, pp. 23328-39, 2005 (PubMed).

Cheng, Ritsick, Lambeth: "Nox3 regulation by NOXO1, p47phox, and p67phox." dans: The Journal of biological chemistry, Vol. 279, Issue 33, pp. 34250-5, 2004 (PubMed).

Cheng, Cao, Xu, van Meir, Lambeth: "Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5." dans: Gene, Vol. 269, Issue 1-2, pp. 131-40, 2001 (PubMed).

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