DOK1 anticorps

N° du produit ABIN966766

Cet anticorps Lapin Polyclonal détecte spécifiquement DOK1 dans IHC. Il présente une réactivité envers Humain, Souris et Rat et a été mentionné dans 4+ publications.

Aperçu rapide pour DOK1 anticorps (ABIN966766)

Antigène: DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOK1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-DOK1 anticorps

Specificité: P62Dok (Ab-362) antibody detects endogenous levels of total p62Dok protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human p62Dok around the phosphorylation site of tyrosine 362 (P-I-YP-D-E).

Information d'application

Indications d'application: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-DOK1 (ABIN966766)

Kato, Takai, Kudo: "The pre-B cell receptor signaling for apoptosis is negatively regulated by Fc gamma RIIB." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 2, pp. 629-34, (2002) (PubMed).

Songyang, Yamanashi, Liu, Baltimore: "Domain-dependent function of the rasGAP-binding protein p62Dok in cell signaling." dans: The Journal of biological chemistry, Vol. 276, Issue 4, pp. 2459-65, (2001) (PubMed).

Némorin, Duplay: "Evidence that Llck-mediated phosphorylation of p56dok and p62dok may play a role in CD2 signaling." dans: The Journal of biological chemistry, Vol. 275, Issue 19, pp. 14590-7, (2000) (PubMed).

Tanaka, Kami, Ogawa, Machida, Takahashi, Ichikawa, Yuji, Izutsu, Asai, Kanda, Honda, Mitani, Chiba, Hirai, Yazaki, Sasaki, Sasaki, Mineishi: "Hyperacute graft-versus-host disease and NKT cells." dans: American journal of hematology, Vol. 63, Issue 1, pp. 60-1, (2000) (PubMed).

Détails sur DOK1

Antigène: DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))

Autre désignation: p62Dok