PPARG anticorps

N° du produit ABIN966887

Il existe 3+ publications pour ce produit. L’anticorps anti-PPARG Monoclonal est utilisé pour la détection de PPARG dans des échantillons de Humain. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour PPARG anticorps (ABIN966887)

Antigène: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp PPARG est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-PPARG anticorps

Specificité: Ni-NTA purified truncated recombinant PPARG expressed in E. Coli strain BL21 (DE3)

Purification: Crude ascites.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
IF : 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: -20 °C

Références pour anticorps anti-PPARG (ABIN966887)

Yang, Ma, Ma, Fogo: "Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis." dans: Kidney international, Vol. 69, Issue 10, pp. 1756-64, (2006) (PubMed).

Weng, Chen, Pinzone, Ringel, Chen: "Beyond peroxisome proliferator-activated receptor gamma signaling: the multi-facets of the antitumor effect of thiazolidinediones." dans: Endocrine-related cancer, Vol. 13, Issue 2, pp. 401-13, (2006) (PubMed).

Ahdjoudj, Kaabeche, Holy, Fromigué, Modrowski, Zérath, Marie: "Transforming growth factor-beta inhibits CCAAT/enhancer-binding protein expression and PPARgamma activity in unloaded bone marrow stromal cells." dans: Experimental cell research, Vol. 303, Issue 1, pp. 138-47, (2004) (PubMed).

Détails sur PPARG

Antigène: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Autre désignation: PPARG

Sujet: PPAR gamma(PPARG), which encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. Three subtypes of PPARs are known: PPAR-alpha, PPARdelta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

ID gène: 5468

Pathways: Signalisation MAPK, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation