Retinoblastoma 1 anticorps

N° du produit ABIN966954

Cité dans 3 publications. Cet anticorps anti-Retinoblastoma 1 Polyclonal Lapin (ABIN966954) détecte spécifiquement Retinoblastoma 1 dans IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Retinoblastoma 1 anticorps (ABIN966954)

Antigène: Retinoblastoma 1 (RB1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Retinoblastoma 1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-Retinoblastoma 1 anticorps

Specificité: Rb (Ab-795) antibody detects endogenous levels of total Rb protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human Rb around the phosphorylation site of serine 795 (P-S-SP-P-L).

Information d'application

Indications d'application: WB: 1:500~1:1000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-Retinoblastoma 1 (ABIN966954)

Roesch, Becker, Meyer, Hafner, Wild, Landthaler, Vogt: "Overexpression and hyperphosphorylation of retinoblastoma protein in the progression of malignant melanoma." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 18, Issue 4, pp. 565-72, (2005) (PubMed).

Knudsen, Wang: "Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation." dans: Molecular and cellular biology, Vol. 17, Issue 10, pp. 5771-83, (1997) (PubMed).

Knudsen, Wang: "Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites." dans: The Journal of biological chemistry, Vol. 271, Issue 14, pp. 8313-20, (1996) (PubMed).

Détails sur Retinoblastoma 1

Antigène: Retinoblastoma 1 (RB1)

Autre désignation: Rb

Pathways: Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy