Retinoblastoma 1 anticorps (RB1)

Details for Product anti-RB1 Antibody No. ABIN966955, Fournisseur: Connectez-vous pour afficher
Antigène
  • OSRC
  • RB
  • p105-Rb
  • pRb
  • pp110
  • DRB1
  • Rb
  • Rb-1
  • P105-RB
  • PP110
  • RB11
  • zgc:154147
  • RB transcriptional corepressor 1
  • RNA binding motif protein 45
  • retinoblastoma 1
  • RB1
  • RBM45
  • Rb1
  • rb1
Reactivité
Humain, Souris, Rat (Rattus)
631
342
236
10
9
8
8
5
5
4
4
3
3
3
2
Hôte
Lapin
465
167
1
Clonalité
Polyclonal
Conjugué
Cet anticorp Retinoblastoma 1 est non-conjugé
28
26
26
16
14
14
14
13
7
7
7
7
7
7
7
7
7
5
5
5
5
5
5
5
5
3
2
1
Application
Immunohistochemistry (IHC)
397
236
169
167
94
91
49
37
30
24
10
9
7
7
6
2
1
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène The antiserum was produced against synthesized non-phosphopeptide derived from human Rb around the phosphorylation site of serine 807 (Y-I-SP-P-L).
Specificité Rb (Ab-807) antibody detects endogenous levels of total Rb protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Autre désignation Rb (RB1 Antibody Extrait)
Pathways Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
Indications d'application WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Produit citée dans: Roesch, Becker, Meyer, Hafner, Wild, Landthaler, Vogt: "Overexpression and hyperphosphorylation of retinoblastoma protein in the progression of malignant melanoma." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 18, Issue 4, pp. 565-72, 2005 (PubMed).

Knudsen, Wang: "Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation." dans: Molecular and cellular biology, Vol. 17, Issue 10, pp. 5771-83, 1997 (PubMed).

Knudsen, Wang: "Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites." dans: The Journal of biological chemistry, Vol. 271, Issue 14, pp. 8313-20, 1996 (PubMed).

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